Specialty

Analytical chemistry, Hygiene and public health

Works

Original papers

1 Shibuya T, Sato A, Nishimoto-Kusunose S, Yoshizawa K, Higashi T. Further evidence for blood-to-brain influx of unconjugated bile acids by passive diffusion: Determination of their brain-to-serum concentration ratios in rats by LC/MS/MS. Steroids. 2024 Apr;204:109397. doi: 10.1016/j.steroids.2024.109397.

2 Nishimoto-Kusunose S, Hirakawa A, Tanaka A, Yoshizawa K, Makino K, Takahashi H, Higashi T. Drugs possessing aryloxypropanamine pharmacophore, duloxetine, dapoxetine and propranolol, increase allopregnanolone in rat brain: Possible involvement of allopregnanolone in their central nervous system effects. Steroids. 2023 Oct;198:109272. doi: 10.1016/j.steroids.2023.109272.

3 Shibuya T, Nishimoto-Kusunose S, Hirakawa A, Yoshizawa K, Higashi T. LC/ESI-MS/MS analysis of progesterone-derived steroids produced in SH-SY5Y cells. Med Mass Spectrom. 2023 Jun;7(1):60-70. doi: 10.24508/mms.2023.06.007.

4 Higashi T, Aso S, Horisaki H, Ito T, Tanaka S, Nishimoto-Kusunose S, Ogawa S, Kato K, Ide H. Evaluation of thumbnail clipping as a specimen for retrospectively assessing average production of testosterone. Clin Chim Acta. 2023 Jan 1;538:157-163. doi: 10.1016/j.cca.2022.11.019.

Reviews

1 Takada K, Hagiwara Y, Togashi M, Kittaka A, Kawagoe F, Uesugi M, Nishimoto-Kusunose S, Higashi T. 23,25-Dihydroxyvitamin D3 is liberated as a major vitamin D3 metabolite in human urine after treatment with β-glucuronidase: Quantitative comparison with 24,25-dihydroxyvitamin D3 by LC/MS/MS. J Steroid Biochem Mol Biol. 2022 Oct;223:106133. doi: 10.1016/j.jsbmb.2022.106133.

2 Fujimura S, Ito T, Ogawa S, Ishige T, Nishimoto-Kusunose S, Higashi T. An LC/MS/MS method for quantifying testosterone and dehydroepiandrosterone sulfate in four different serum samples during a single run. Anal Sci. 2022 Jan;38(1):167-173. doi: 10.2116/analsci.21P268.

Books

1 Nishimoto-Kusunose S, Sawa M, Inaba Y, Ushiyama A, Ishii K, Hattori K, Ogasawara Y. Exposure to aerosol extract from heated tobacco products causes a drastic decrease of glutathione and protein carbonylation in human lung epithelial cells. Biochem Biophys Res Commun. 2022 Jan 22;589:92-99. doi: 10.1016/j.bbrc.2021.12.004.

2 Ohta A, Hobo W, Ogawa S, Sugiura Y, Nishikawa T, Nishimoto K, Nishimoto-Kusunose S, Higashi T. A method for determination of aldosterone concentrations of six adrenal venous serum samples during a single LC/ESI-MS/MS run using a sextet of Girard reagents. J Pharm Biomed Anal. 2022 Jan 5;207:114423. doi: 10.1016/j.jpba.2021.114423.

3 Koike S, Miyaji Y, Sano H, Aikawa N, Kai M, Kasahara S, Suzuki T, Nishimoto-Kusunose S, Ogasawara Y. Simultaneous Determination of Five Bile Acids as Potential Biomarkers for Alzheimer’s Disease in Mouse Brain and Plasma. Anal Sci. 2021 Aug 10;37(8):1165-1170. doi: 10.2116/analsci.20P429.

Conference presentations

1 Kusunose S, Inaba Y, Bekki K, Ushiyama A. Determination of reactive oxygen species in aerosol of heated tobacco products by DCFH assay. The 144th Annual Meeting of the Pharmaceutical Society of Japan; 2024.3.28-31; Yokohama, Japan. Program book.